General Information
SPKB ID SPKB00381
Signal sequence MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTA
Length 34
Organism Artificial
UniProt ID NA,
Motif 1..34
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00381.cif
Physicochemical Information
Molecular weight 3919.57694
Aliphatic index 77.64705882
Isoelectric point 8.55741055
Charge (pH=7) 1.028687175
Topological polar surface area 1435.82
Aromaticity 0.117647059
Average rotatable bonds 3.235294118
Number of hydrogen bond donors 50
Number of hydrogen bond acceptors 50
X logP energy -10.13406
Hydropathy
Literature Information
Title Tumor vaccine signal peptide for enhancing HLA class I molecular antigen presentation and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN117756917A,