General Information
SPKB ID SPKB00380
Signal sequence MLLSVPLLLGLLGLAVA
Length 17
Organism Artificial
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency The production of anti-cTnI antibodies has reached 400-450mg/L
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00380.cif
Physicochemical Information
Molecular weight 1693.20454
Aliphatic index 229.4117647
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 540.36
Aromaticity 0
Average rotatable bonds 3.176470588
Number of hydrogen bond donors 18
Number of hydrogen bond acceptors 20
X logP energy 0.3901
Hydropathy
Literature Information
Title Tumor vaccine signal peptide for enhancing HLA class I molecular antigen presentation and application thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN117756917A,