General Information
SPKB ID SPKB00378
Signal sequence MQRVNMIMAESPGLITICLLGYLLSAEC
Length 28
Organism Homo sapiens (Human)
UniProt ID P00740,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00378.cif
Physicochemical Information
Molecular weight 3070.74704
Aliphatic index 128.9285714
Isoelectric point 4.25806771
Charge (pH=7) -1.123268612
Topological polar surface area 1143.83
Aromaticity 0.035714286
Average rotatable bonds 3.642857143
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 43
X logP energy -8.11213
Hydropathy 
Literature Information
Title Isolated nucleic acids encoding fusion proteins based on FVIII-BDD and heterologous signal peptides and uses thereof
DOI NA,
Publication Year 2024
PubMed ID NA,
Patent ID CN117402901A,
