Peptide-Information

General Information

SPKB ID SPKB00377

Signal sequence MQIELSTCFFLCLLRFCFS

Length 19

Organism Homo sapiens (Human)

UniProt ID P00451,

Motif 1..19

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 7KWO,

Predicted Structure ID SPKB00377.cif

Structure SPKB00377.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2301.82284

Aliphatic index 102.6315789

Isoelectric point 6.068922519

Charge (pH=7) -0.186168037

Topological polar surface area 790.1

Aromaticity 0.210526316

Average rotatable bonds 3.894736842

Number of hydrogen bond donors 31

Number of hydrogen bond acceptors 30

X logP energy -3.37253

Hydropathy

Literature Information

Title Isolated nucleic acids encoding fusion proteins based on FVIII-BDD and heterologous signal peptides and uses thereof

DOI NA,

Publication Year 2024

PubMed ID NA,