SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00376

Signal sequence   MSKKQKKPEQIHRRDDLKWGAMAGAAVAIGASGLGGLAPLVQTAAKP

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  DAEase activity: 185.1U/mL??

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00376.cif

Structure  SPKB00376.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4854.71294

Aliphatic index  81.27659574

Isoelectric point  11.07852613

Charge (pH=7)   5.089784656

Topological polar surface area  2001.8

Aromaticity  0.021276596

Average rotatable bonds  3.510638298

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  68

X logP energy  -20.75356

Hydropathy 



Literature Information


Title  Signal peptide and mutant RBS for improving secretory expression of D-psicose-3-epimerase

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN117343922A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.