SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00375

Signal sequence   MSKEQKKPEQIHRRDILKWGAMAGAAVAIGASGLGGLAPLVQTAAKP

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  DAEase activity: 160U/mL??

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00375.cif

Structure  SPKB00375.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4853.72514

Aliphatic index  89.57446809

Isoelectric point  10.9575815

Charge (pH=7)   4.091408328

Topological polar surface area  1975.78

Aromaticity  0.021276596

Average rotatable bonds  3.489361702

Number of hydrogen bond donors  67

Number of hydrogen bond acceptors  67

X logP energy  -19.44636

Hydropathy 



Literature Information


Title  Signal peptide and mutant RBS for improving secretory expression of D-psicose-3-epimerase

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  CN117343922A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.