General Information
SPKB ID SPKB00367
Signal sequence MRFPSIFTAVLFAASSALAAPVNTTTEDETAQIPAEAVIGYLDLEGDFDVAVLPFSASIAAKEEGVSLEKREAEAEAEPK
Length 80
Organism Artificial
UniProt ID NA,
Motif 1..80
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Nanobody expression: 10.2mg
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00367.cif
Physicochemical Information
Molecular weight 8416.40784
Aliphatic index 90.5
Isoelectric point 3.793317498
Charge (pH=7) -9.982445552
Topological polar surface area 3408.57
Aromaticity 0.075
Average rotatable bonds 3.4
Number of hydrogen bond donors 114
Number of hydrogen bond acceptors 116
X logP energy -32.92316
Hydropathy 
Literature Information
Title Mutant alpha-factor signal peptide as well as coding gene, expression vector and application thereof
DOI NA,
Publication Year 2023
PubMed ID NA,
Patent ID CN116854792A,
