Peptide-Information

General Information

SPKB ID SPKB00366

Signal sequence MRFPSIFLAVLFAASSALAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKREA

Length 87

Organism Artificial

UniProt ID NA,

Motif 1..87

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency Nanobody expression: 10.47mg

Type Sec/SPI

Structure Information

PDB ID 7XOI,

Predicted Structure ID SPKB00366.cif

Structure SPKB00366.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 9151.26084

Aliphatic index 98.85057471

Isoelectric point 3.792060839

Charge (pH=7) -7.987475887

Topological polar surface area 3736.42

Aromaticity 0.08045977

Average rotatable bonds 3.402298851

Number of hydrogen bond donors 126

Number of hydrogen bond acceptors 127

X logP energy -39.49266

Hydropathy

Literature Information

Title Mutant alpha-factor signal peptide as well as coding gene, expression vector and application thereof

DOI NA,

Publication Year 2023

PubMed ID NA,