Peptide-Information

General Information

SPKB ID SPKB00361

Signal sequence MKRMQLLSCIALSLALVTNS

Length 20

Organism Artificial

UniProt ID NA,

Motif 1..20

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency CAR expression efficiency: 35.5%

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB00361.cif

Structure SPKB00361.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2192.72164

Aliphatic index 141.5

Isoelectric point 9.833242293

Charge (pH=7) 1.935711238

Topological polar surface area 871.24

Aromaticity 0

Average rotatable bonds 3.8

Number of hydrogen bond donors 32

Number of hydrogen bond acceptors 32

X logP energy -8.09123

Hydropathy

Literature Information

Title CD19 targeting chimeric antigen receptor with optimized signal peptide sequence and application of CD19 targeting chimeric antigen receptor

DOI NA,

Publication Year 2023

PubMed ID NA,