Peptide-Information

General Information

SPKB ID SPKB00360

Signal sequence MYRMQLLSCIALSLALVTNS

Length 20

Organism Artificial

UniProt ID NA,

Motif 1..20

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency CAR expression efficiency: 33.9%

Type Sec/SPI

Structure Information

PDB ID 6LX3,

Predicted Structure ID SPKB00360.cif

Structure SPKB00360.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2227.72354

Aliphatic index 141.5

Isoelectric point 8.527213491

Charge (pH=7) 0.935155858

Topological polar surface area 865.45

Aromaticity 0.05

Average rotatable bonds 3.7

Number of hydrogen bond donors 32

Number of hydrogen bond acceptors 32

X logP energy -7.27193

Hydropathy

Literature Information

Title CD19 targeting chimeric antigen receptor with optimized signal peptide sequence and application of CD19 targeting chimeric antigen receptor

DOI NA,

Publication Year 2023

PubMed ID NA,