SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00359

Signal sequence   MKLLLLTLVVVTLVCLDLGYT

Length  21

Organism  Artificial

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00359.cif

Structure  SPKB00359.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2320.95814

Aliphatic index  203.8095238

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  789.56

Aromaticity  0.047619048

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -0.9042

Hydropathy 



Literature Information


Title  Snake toxin signal peptide for improving secretory expression quantity of recombinant antibody as well as product and application of snake toxin signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116334137A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.