SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00358

Signal sequence   MTRLTVLALLALLLASSRA

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Thrombopoietin: 26.3mg/L

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00358.cif

Structure  SPKB00358.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2013.51304

Aliphatic index  180

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  791.84

Aromaticity  0

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -5.79116

Hydropathy 



Literature Information


Title  Signal peptide, nucleic acid fragment, recombinant expression vector, host cell and application thereof

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116284246A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.