SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00357

Signal sequence   MGVKVLFALICIAVAEA

Length  17

Organism  Artificial

UniProt ID  NA,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  A29L antigen production: 161.78mg/L

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00357.cif

Structure  SPKB00357.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1748.21534

Aliphatic index  166.4705882

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  592.24

Aromaticity  0.058823529

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  22

X logP energy  -1.0621

Hydropathy 



Literature Information


Title  Application of luciferase signal peptide, fusion protein containing luciferase signal peptide and preparation method of fusion protein

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116240182A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.