General Information
SPKB ID SPKB00307
Signal sequence MEWSWVFLFFLSLTGIHC
Length 18
Organism Artificial
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Terminal extension ratio less than 3%
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00307.cif
Physicochemical Information
Molecular weight 2216.64304
Aliphatic index 102.7777778
Isoelectric point 5.36107726
Charge (pH=7) -0.971306203
Topological polar surface area 716.27
Aromaticity 0.277777778
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 26
X logP energy 0.1667
Hydropathy 
Literature Information
Title Signal peptides for reducing terminal heterogeneity of heterologous polypeptides
DOI NA,
Publication Year 2023
PubMed ID NA,
Patent ID CN116234814A,
