General Information
SPKB ID SPKB00261
Signal sequence MSKVPVALVWLVLLLLTVQVGVTAG
Length 25
Organism Artificial
UniProt ID NA,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Increase human IGFBP3 expression by 15 times
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00261.cif
Physicochemical Information
Molecular weight 2607.27694
Aliphatic index 182.8
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 898.52
Aromaticity 0.04
Average rotatable bonds 3.28
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 32
X logP energy -2.6636
Hydropathy 
Literature Information
Title Signal peptide and application thereof
DOI NA,
Publication Year 2023
PubMed ID NA,
Patent ID CN116102625A,
