SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00259

Signal sequence   MKKRRKICYCNTALLLMILLAGCT

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 3260U/L

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00259.cif

Structure  SPKB00259.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2757.52944

Aliphatic index  122.0833333

Isoelectric point  10.15364277

Charge (pH=7)   4.810318013

Topological polar surface area  1038.26

Aromaticity  0.041666667

Average rotatable bonds  4

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -6.66296

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.