SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00257

Signal sequence   MLLKRRIGLLLSMVGVFMLLAGCS

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 540U/L

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00257.cif

Structure  SPKB00257.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2622.38884

Aliphatic index  158.3333333

Isoelectric point  11.48119255

Charge (pH=7)   2.935707927

Topological polar surface area  922.9

Aromaticity  0.041666667

Average rotatable bonds  3.791666667

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -3.78446

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.