SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00256

Signal sequence   MRIQKRRTHVENILRILLPPIMILSLILPTPPIHA

Length  35

Organism  Artificial

UniProt ID  NA,

Motif  1..35



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 910U/L

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00256.cif

Structure  SPKB00256.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4095.11224

Aliphatic index  156

Isoelectric point  12.50839109

Charge (pH=7)   4.181269325

Topological polar surface area  1523.92

Aromaticity  0

Average rotatable bonds  3.771428571

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  51

X logP energy  -6.93282

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.