SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00254

Signal sequence   MFESEAELRRIRIALVWIAVFLLFGACG

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 20U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00254.cif

Structure  SPKB00254.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3211.87684

Aliphatic index  132.5

Isoelectric point  6.434085373

Charge (pH=7)   -0.058674982

Topological polar surface area  1182.64

Aromaticity  0.142857143

Average rotatable bonds  3.75

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  38

X logP energy  -4.02349

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.