SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00253

Signal sequence   MKFVKRRIIALVTILMLSVTSLFALQPSAKA

Length  31

Organism  Artificial

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 480U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00253.cif

Structure  SPKB00253.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3447.33134

Aliphatic index  141.6129032

Isoelectric point  12.54607567

Charge (pH=7)   4.997092575

Topological polar surface area  1273.63

Aromaticity  0.064516129

Average rotatable bonds  3.774193548

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  45

X logP energy  -7.22596

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.