SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00252

Signal sequence   MDRRDNGGQYMDKRFAVVLAAGQGTRMKSKLYKVLHP

Length  37

Organism  Artificial

UniProt ID  NA,

Motif  1..37



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Glutaminase activity: 440U/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00252.cif

Structure  SPKB00252.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4238.96014

Aliphatic index  63.24324324

Isoelectric point  10.88409083

Charge (pH=7)   5.087338634

Topological polar surface area  1804.58

Aromaticity  0.081081081

Average rotatable bonds  3.945945946

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  60

X logP energy  -17.81402

Hydropathy 



Literature Information


Title  Method for improving secretory expression of protein glutaminase by using NprB signal peptide

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN116042589A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.