SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00251

Signal sequence   GTTRLLSGHTCFTLTGLLGTLVTMGLLT

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  GPI anchor

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  3IYP,

Predicted Structure ID  SPKB00251.cif

Structure  SPKB00251.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2878.43814

Aliphatic index  121.7857143

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  1121.67

Aromaticity  0.035714286

Average rotatable bonds  3.321428571

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -12.13693

Hydropathy 



Literature Information


Title  Signal peptide sequence capable of displaying protein on exosome membrane through GPI anchoring method

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN115850389A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.