General Information
SPKB ID SPKB00250
Signal sequence MALLHKNMKHLWFFLLLVAAPRWVLS
Length 26
Organism Artificial
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Nivolumab titer: 6.1g/L
Type Sec/SPI
Structure Information
PDB ID 7MX8,
Predicted Structure ID SPKB00250.cif
Physicochemical Information
Molecular weight 3135.91404
Aliphatic index 138.8461538
Isoelectric point 11.82306892
Charge (pH=7) 3.179209102
Topological polar surface area 1048.23
Aromaticity 0.153846154
Average rotatable bonds 3.807692308
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 36
X logP energy 0.47907
Hydropathy
Literature Information
Title Novel combination of TIS sequences and signal peptide sequences for expression of recombinant proteins
DOI NA,
Publication Year 2022
PubMed ID NA,
Patent ID CN115298313A,