SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00249

Signal sequence   MFRLFHNQQKAKTKLKVLLIFQLSVIFSLTAAICLQFSDDTSAA

Length  44

Organism  Artificial

UniProt ID  NA,

Motif  1..44



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase activity: 235.2FU/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00249.cif

Structure  SPKB00249.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4987.93974

Aliphatic index  113.1818182

Isoelectric point  10.33758422

Charge (pH=7)   3.026628196

Topological polar surface area  1940.94

Aromaticity  0.113636364

Average rotatable bonds  3.863636364

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  67

X logP energy  -15.24293

Hydropathy 



Literature Information


Title  Signal peptide for improving secretion efficiency of nattokinase and application of signal peptide

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  CN114574470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.