SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00248

Signal sequence   MEERSQRRKKKRKLKKWVKVVAGLMAFLVIAAGSVGAYAA

Length  40

Organism  Artificial

UniProt ID  NA,

Motif  1..40



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase activity: 225.4FU/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00248.cif

Structure  SPKB00248.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4476.46094

Aliphatic index  92.75

Isoelectric point  11.79668912

Charge (pH=7)   8.998605649

Topological polar surface area  1822.13

Aromaticity  0.075

Average rotatable bonds  3.975

Number of hydrogen bond donors  67

Number of hydrogen bond acceptors  60

X logP energy  -13.83962

Hydropathy 



Literature Information


Title  Signal peptide for improving secretion efficiency of nattokinase and application of signal peptide

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  CN114574470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.