SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00247

Signal sequence   MKKIWIGMLAAAVLLLMVPKVSLADAA

Length  27

Organism  Artificial

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase activity: 208.3FU/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00247.cif

Structure  SPKB00247.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2854.65034

Aliphatic index  155.5555556

Isoelectric point  10.50691891

Charge (pH=7)   1.997545682

Topological polar surface area  962.51

Aromaticity  0.037037037

Average rotatable bonds  3.518518519

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -1.6119

Hydropathy 



Literature Information


Title  Signal peptide for improving secretion efficiency of nattokinase and application of signal peptide

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  CN114574470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.