SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00246

Signal sequence   MKKRKRRNFKRFIAAFLVLALMISLVPADVLAA

Length  33

Organism  Artificial

UniProt ID  NA,

Motif  1..33



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase activity: 207.7FU/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00246.cif

Structure  SPKB00246.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3788.75034

Aliphatic index  127.2727273

Isoelectric point  12.53169954

Charge (pH=7)   6.997237403

Topological polar surface area  1438.03

Aromaticity  0.090909091

Average rotatable bonds  3.939393939

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  47

X logP energy  -7.02602

Hydropathy 



Literature Information


Title  Signal peptide for improving secretion efficiency of nattokinase and application of signal peptide

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  CN114574470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.