SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00245

Signal sequence   MRSKKLWISLLFALTLIFTMAFSNMSVQAA

Length  30

Organism  Artificial

UniProt ID  NA,

Motif  1..30



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Nattokinase activity: 171FU/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00245.cif

Structure  SPKB00245.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3420.19284

Aliphatic index  114

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1244.51

Aromaticity  0.133333333

Average rotatable bonds  3.8

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  45

X logP energy  -7.37983

Hydropathy 



Literature Information


Title  Signal peptide for improving secretion efficiency of nattokinase and application of signal peptide

DOI  NA,

Publication Year  2022

PubMed ID  NA,

Patent ID  CN114574470A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.