General Information
SPKB ID SPKB00243
Signal sequence MDWTWRVFCLLAVTPGVHS
Length 19
Organism Artificial
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency GLP-1-Fc fusion protein: 2.6g/L
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00243.cif
Physicochemical Information
Molecular weight 2218.61924
Aliphatic index 92.10526316
Isoelectric point 7.359696704
Charge (pH=7) 0.027361847
Topological polar surface area 798.48
Aromaticity 0.157894737
Average rotatable bonds 3.368421053
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 28
X logP energy -3.82633
Hydropathy
Literature Information
Title Application of signal peptide in expression of GLP-1 fusion protein
DOI NA,
Publication Year 2022
PubMed ID NA,
Patent ID CN114539357A,