Peptide-Information

General Information

SPKB ID SPKB00242

Signal sequence MDWTWRVFCLLAVTPGVHP

Length 19

Organism Artificial

UniProt ID NA,

Motif 1..19

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency GLP-1-Fc fusion protein: 2.9g/L

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB00242.cif

Structure SPKB00242.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2228.65774

Aliphatic index 92.10526316

Isoelectric point 7.359696704

Charge (pH=7) 0.027361847

Topological polar surface area 769.46

Aromaticity 0.157894737

Average rotatable bonds 3.263157895

Number of hydrogen bond donors 28

Number of hydrogen bond acceptors 27

X logP energy -2.31243

Hydropathy

Literature Information

Title Application of signal peptide in expression of GLP-1 fusion protein

DOI NA,

Publication Year 2022

PubMed ID NA,