General Information
SPKB ID SPKB00241
Signal sequence MDWTWRVFCLLAVAPGVHP
Length 19
Organism Artificial
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency GLP-1-Fc fusion protein: 3.3g/L
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00241.cif
Physicochemical Information
Molecular weight 2198.63144
Aliphatic index 97.36842105
Isoelectric point 7.359696704
Charge (pH=7) 0.027361847
Topological polar surface area 749.23
Aromaticity 0.157894737
Average rotatable bonds 3.210526316
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 26
X logP energy -1.67333
Hydropathy
Literature Information
Title Application of signal peptide in expression of GLP-1 fusion protein
DOI NA,
Publication Year 2022
PubMed ID NA,
Patent ID CN114539357A,