SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00230

Signal sequence   VARGRTDEISTDVSEAN

Length  17

Organism  Artificial

UniProt ID  NA,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00230.cif

Structure  SPKB00230.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1819.90294

Aliphatic index  68.82352941

Isoelectric point  4.105241229

Charge (pH=7)   -1.997579109

Topological polar surface area  925.93

Aromaticity  0

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  29

X logP energy  -13.98846

Hydropathy 



Literature Information


Title  Signal peptide related sequence and application thereof in protein synthesis

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN113481226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.