SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00226

Signal sequence   KTHIVSSVTTTLLLGSIL

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00226.cif

Structure  SPKB00226.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1883.25894

Aliphatic index  162.2222222

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  754.33

Aromaticity  0

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -7.5452

Hydropathy 



Literature Information


Title  Signal peptide related sequence and application thereof in protein synthesis

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN113481226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.