SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00225

Signal sequence   KTHIVSSVTTTL

Length  12

Organism  Artificial

UniProt ID  NA,

Motif  1..12



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00225.cif

Structure  SPKB00225.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1286.49124

Aliphatic index  113.3333333

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  559.5

Aromaticity  0

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  21

X logP energy  -7.2621

Hydropathy 



Literature Information


Title  Signal peptide related sequence and application thereof in protein synthesis

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN113481226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.