SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00224

Signal sequence   NCSAHCIKKALPAQWIRC

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00224.cif

Structure  SPKB00224.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2042.46564

Aliphatic index  81.66666667

Isoelectric point  8.987441462

Charge (pH=7)   2.902375864

Topological polar surface area  814.05

Aromaticity  0.055555556

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  29

X logP energy  -7.52223

Hydropathy 



Literature Information


Title  Signal peptide related sequence and application thereof in protein synthesis

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN113481226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.