SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00222

Signal sequence   LTTVLPNVATLNSMFAL

Length  17

Organism  Artificial

UniProt ID  NA,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00222.cif

Structure  SPKB00222.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1805.16264

Aliphatic index  137.6470588

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  687.23

Aromaticity  0.058823529

Average rotatable bonds  3.235294118

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -5.9212

Hydropathy 



Literature Information


Title  Signal peptide related sequence and application thereof in protein synthesis

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN113481226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.