SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00218

Signal sequence   MKYLLPTTAAGLLLLAAQPATAK

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Crude enzyme activity: 153.2%

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00218.cif

Structure  SPKB00218.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2356.89254

Aliphatic index  127.826087

Isoelectric point  10.24760792

Charge (pH=7)   1.996543817

Topological polar surface area  861.99

Aromaticity  0.043478261

Average rotatable bonds  3.217391304

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  32

X logP energy  -5.529

Hydropathy 



Literature Information


Title  Signal peptide mutant and application thereof

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN112852800A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.