SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00216

Signal sequence   MKYLLPTAAAGLLLLAAQPTMAM

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  Crude enzyme activity: 212.3%

Type  NA



Structure Information


PDB ID  8H83,

Predicted Structure ID  SPKB00216.cif

Structure  SPKB00216.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2389.99854

Aliphatic index  127.826087

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  815.74

Aromaticity  0.043478261

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  32

X logP energy  -3.5326

Hydropathy 



Literature Information


Title  Signal peptide mutant and application thereof

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN112852800A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.