SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00208

Signal sequence   MSKKQHKPKQIHRRDILKWGAMAGAAVA

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase amylase activity by 1.5 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00208.cif

Structure  SPKB00208.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3157.79484

Aliphatic index  70

Isoelectric point  11.87839536

Charge (pH=7)   6.178767174

Topological polar surface area  1310.99

Aromaticity  0.035714286

Average rotatable bonds  3.928571429

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  44

X logP energy  -11.51796

Hydropathy 



Literature Information


Title  Signal peptide mutant for improving extracellular production level of bacillus subtilis recombinant protein and application

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN112409464A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.