SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00200

Signal sequence   MSDKQHKPEQIHRRDILKWGAMAGAAVA

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase amylase activity by 1.2 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00200.cif

Structure  SPKB00200.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3145.65074

Aliphatic index  70

Isoelectric point  10.49455454

Charge (pH=7)   2.181578848

Topological polar surface area  1333.55

Aromaticity  0.035714286

Average rotatable bonds  3.821428571

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  44

X logP energy  -12.43646

Hydropathy 



Literature Information


Title  Signal peptide mutant for improving extracellular production level of bacillus subtilis recombinant protein and application

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  CN112409464A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.