General Information
SPKB ID SPKB00196
Signal sequence MSALLILALVGAAVVWA
Length 17
Organism Artificial
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Increase human CD73 by 8 times
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00196.cif
Physicochemical Information
Molecular weight 1698.13994
Aliphatic index 195.2941176
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 564.94
Aromaticity 0.058823529
Average rotatable bonds 3.058823529
Number of hydrogen bond donors 20
Number of hydrogen bond acceptors 20
X logP energy -0.4461
Hydropathy 
Literature Information
Title Signal peptide for improving secretory expression of recombinant protein in mammalian cells and application thereof
DOI NA,
Publication Year 2020
PubMed ID NA,
Patent ID CN112028972A,
