General Information
SPKB ID SPKB00180
Signal sequence MFKSLCMLIGSCLLSSVLKA
Length 20
Organism Artificial
UniProt ID NA,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Increase thermoresistant mannanase expression by 2.64 times
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00180.cif
Physicochemical Information
Molecular weight 2144.73534
Aliphatic index 136.5
Isoelectric point 8.821677593
Charge (pH=7) 1.8734448
Topological polar surface area 749.18
Aromaticity 0.05
Average rotatable bonds 3.7
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 31
X logP energy -4.9709
Hydropathy 
Literature Information
Title Modified signal peptide for guiding secretory expression of heat-resistant mannase, recombinant plasmid, genetically engineered bacterium, production method and application
DOI NA,
Publication Year 2020
PubMed ID NA,
Patent ID CN111471087A,
