SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00175

Signal sequence   MKKGIIRFLLVSFVLFFALSTGITGVQAAPA

Length  31

Organism  Artificial

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline protease activity: 4508U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00175.cif

Structure  SPKB00175.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3297.04844

Aliphatic index  129.0322581

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1165.48

Aromaticity  0.129032258

Average rotatable bonds  3.451612903

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -6.03013

Hydropathy 



Literature Information


Title  Signal peptide mutant capable of enhancing expression levels of exogenous alkaline protease, and construction method and applications thereof

DOI  NA,

Publication Year  2020

PubMed ID  NA,

Patent ID  CN111153968A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.