SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00173

Signal sequence   MRSGLKKKAGFWKKTAVSSLIFTMFFTLMMSGTALA

Length  36

Organism  Artificial

UniProt ID  NA,

Motif  1..36



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline protease activity: 1300U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00173.cif

Structure  SPKB00173.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3987.89694

Aliphatic index  73.33333333

Isoelectric point  12.05455268

Charge (pH=7)   5.996505819

Topological polar surface area  1451.45

Aromaticity  0.138888889

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  55

X logP energy  -10.66553

Hydropathy 



Literature Information


Title  Signal peptide mutant capable of enhancing expression levels of exogenous alkaline protease, and construction method and applications thereof

DOI  NA,

Publication Year  2020

PubMed ID  NA,

Patent ID  CN111153968A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.