SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00172

Signal sequence   MKRVLLILVTGLFMSLCGITSSASA

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline protease activity: 7329U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00172.cif

Structure  SPKB00172.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2612.24284

Aliphatic index  140.4

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  971.02

Aromaticity  0.04

Average rotatable bonds  3.52

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -8.22743

Hydropathy 



Literature Information


Title  Signal peptide mutant capable of enhancing expression levels of exogenous alkaline protease, and construction method and applications thereof

DOI  NA,

Publication Year  2020

PubMed ID  NA,

Patent ID  CN111153968A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.