SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00171

Signal sequence   MIQKRKRTVSFRLVLMCTLLFVSLPITKASA

Length  31

Organism  Artificial

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Alkaline protease activity: 3287U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00171.cif

Structure  SPKB00171.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3552.44574

Aliphatic index  122.5806452

Isoelectric point  12.26282319

Charge (pH=7)   5.935114548

Topological polar surface area  1355.76

Aromaticity  0.064516129

Average rotatable bonds  3.903225806

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  48

X logP energy  -9.73799

Hydropathy 



Literature Information


Title  Signal peptide mutant capable of enhancing expression levels of exogenous alkaline protease, and construction method and applications thereof

DOI  NA,

Publication Year  2020

PubMed ID  NA,

Patent ID  CN111153968A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.