SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00168

Signal sequence   MRIFKKAVFVIMISFLIATVNVNTAHAMFAKRFKTSLLPLFAGFLLLFHLVLAGPAAASAETANKSNELT

Length  70

Organism  Artificial

UniProt ID  NA,

Motif  1..70



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Keratinase activity: 226.34U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00168.cif

Structure  SPKB00168.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7626.19544

Aliphatic index  115.8571429

Isoelectric point  11.33635283

Charge (pH=7)   5.181870935

Topological polar surface area  2793.93

Aromaticity  0.114285714

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  97

Number of hydrogen bond acceptors  98

X logP energy  -18.30266

Hydropathy 



Literature Information


Title  Double-signal peptide capable of improving expression quantity of foreign protein as well as construction method and application of double-signal peptide

DOI  NA,

Publication Year  2020

PubMed ID  NA,

Patent ID  CN111087476A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.