General Information
SPKB ID SPKB00158
Signal sequence MKVLALLVTVCFSVASAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKREAEA
Length 87
Organism Artificial
UniProt ID NA,
Motif 1..87
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Enterokinase: 398700U/mL
Type Sec/SPI
Structure Information
PDB ID 7XOI,
Predicted Structure ID SPKB00158.cif
Physicochemical Information
Molecular weight 9091.21834
Aliphatic index 103.2183908
Isoelectric point 3.746891645
Charge (pH=7) -9.047967202
Topological polar surface area 3746.63
Aromaticity 0.057471264
Average rotatable bonds 3.425287356
Number of hydrogen bond donors 127
Number of hydrogen bond acceptors 129
X logP energy -40.53343
Hydropathy
Literature Information
Title Method for increasing secretory expression level of enterokinase through improving signal peptide
DOI NA,
Publication Year 2019
PubMed ID NA,
Patent ID CN110042068A,