SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00158

Signal sequence   MKVLALLVTVCFSVASAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKREAEA

Length  87

Organism  Artificial

UniProt ID  NA,

Motif  1..87



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Enterokinase: 398700U/mL

Type  Sec/SPI



Structure Information


PDB ID  7XOI,

Predicted Structure ID  SPKB00158.cif

Structure  SPKB00158.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  9091.21834

Aliphatic index  103.2183908

Isoelectric point  3.746891645

Charge (pH=7)   -9.047967202

Topological polar surface area  3746.63

Aromaticity  0.057471264

Average rotatable bonds  3.425287356

Number of hydrogen bond donors  127

Number of hydrogen bond acceptors  129

X logP energy  -40.53343

Hydropathy 



Literature Information


Title  Method for increasing secretory expression level of enterokinase through improving signal peptide

DOI  NA,

Publication Year  2019

PubMed ID  NA,

Patent ID  CN110042068A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.