General Information
SPKB ID SPKB00156
Signal sequence MKFSAVSIAAALASLVAAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKREAEA
Length 88
Organism Artificial
UniProt ID NA,
Motif 1..88
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Enterokinase activity: 687,400U/mL
Type Sec/SPI
Structure Information
PDB ID 7XOI,
Predicted Structure ID SPKB00156.cif
Physicochemical Information
Molecular weight 9060.10264
Aliphatic index 100
Isoelectric point 3.746894096
Charge (pH=7) -8.985992486
Topological polar surface area 3775.73
Aromaticity 0.056818182
Average rotatable bonds 3.375
Number of hydrogen bond donors 127
Number of hydrogen bond acceptors 129
X logP energy -42.59933
Hydropathy
Literature Information
Title Method for increasing secretory expression level of enterokinase through improving signal peptide
DOI NA,
Publication Year 2019
PubMed ID NA,
Patent ID CN110042068A,