General Information
SPKB ID SPKB00154
Signal sequence MKFSTALLALAAVATAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKREAEA
Length 86
Organism Artificial
UniProt ID NA,
Motif 1..86
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency Enterokinase: 507000U/mL
Type Sec/SPI
Structure Information
PDB ID 7XOI,
Predicted Structure ID SPKB00154.cif
Physicochemical Information
Molecular weight 8917.94504
Aliphatic index 97.79069767
Isoelectric point 3.746894096
Charge (pH=7) -8.985992486
Topological polar surface area 3717.53
Aromaticity 0.058139535
Average rotatable bonds 3.395348837
Number of hydrogen bond donors 125
Number of hydrogen bond acceptors 127
X logP energy -41.46783
Hydropathy
Literature Information
Title Method for increasing secretory expression level of enterokinase through improving signal peptide
DOI NA,
Publication Year 2019
PubMed ID NA,
Patent ID CN110042068A,